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In Search of Multimodal Neuroimaging Biomarkers of Cognitive Deficits in Schizophrenia

机译:寻找精神分裂症认知功能障碍的多模式神经影像生物标志物。

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摘要

BACKGROUND: The cognitive deficits of schizophrenia are largely resistant to current treatments and thus are a lifelong illness burden. The Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery (MCCB) provides a reliable and valid assessment of cognition across major cognitive domains; however, the multimodal brain alterations specifically associated with MCCB in schizophrenia have not been examined.
机译:背景:精神分裂症的认知缺陷在很大程度上对目前的治疗有抵抗力,因此是终身疾病负担。改善精神分裂症认知(MATRICS)共识认知电池(MCCB)的测量和治疗研究为跨主要认知领域的认知提供了可靠而有效的评估;但是,尚未研究与精神分裂症中MCCB特别相关的多峰脑部改变。

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