Unruptured intracranial aneurysms: some questions answered, many questions remain. Re: Pelz D. CURES and the dilemma of unruptured intracranial aneurysms. Can J Neuro Sci. 2011 Mar;38(2):191-2.

摘要

We read with interest the thoughtful editorial written by Dr. David Pelz1. Dr. Pelz has summarized some of the available data regarding the natural history of unruptured intracranial aneurysms (UIAs), and the morbidity and mortality of surgical clipping and endovascular coiling for these lesions. Dr. Pelz notes several significant concerns regarding the proposed feasibility trial of UIA treatment, the Canadian Unruptured Endovascular versus Surgery Trial (CURES)2. In that study, Dr. Jean Raymond ,and colleagues propose randomization of 260 patients with 3-25 mm UIAs to either surgery or endovascular therapy.