Ductal carcinoma in situ and bilateral atypical ductal hyperplasia in a 23-year-old man with gynecomastia.

摘要

Male breast cancer cases constitute approximately 1 per cent of all breast carcinomas. They are usually diagnosed at older ages with peak incidence at 71 years of age. Risk factors such as family history, age, hormonal status, Klinefelter syndrome, and obesity are very important for the onset of the disease. Male breast carcinomas account for just 0.25 per cent of all estimated new cases of cancer and 0.15 per cent of estimated cancer deaths for males in 2009 in the United States. Between 15 and 29 years of age in males, leukemia, lymphoma, central nervous system, and genital organ malignancies are more common cancers. Breast cancer cases are becoming increasingly uncommon among younger age groups. In addition, carcinoma in situ of the male breast is much more uncommon, especially when coexisting with bilateral gynecomastia. Ductal carcinoma in situ (DCIS) is extremely rare among males and constitutes approximately 5 per cent of all male breast carcinomas. DCIS in a young male is rarely reported and to date, only five cases of gynecomastia and DCIS comorbidity have been described in younger male patients. To the best of our knowledge, more than one focus of DCIS and bilateral widespread atypical ductal epithelial hyper-plasia and gynecomastia has not yet been described in the literature. We describe a new case of multifoci DCIS and bilateral widespread atypical ductal hyperplasia with gynecomastia in a young male.