Palladium-catalyzed stereospecific ring expansion reaction of allenylcyclobutanols with aryl iodides: a novel route to the #alpha#-substituted cyclopentanones with quaternary carbon stereocenters

摘要

Stereoselective synthesis of #alpha#-substituted cyclopentanones with quaternary carbon stereocenters has been achieved by the palladium-catalyzed rearrangemennt of allenylcyclobutanols with aryl iodides.