PREPARATION OF NEW TRIFLUOROMETHYL SUBSTITUTED TRI- AND TETRACYCLIC HETEROCYCLES WITH PEGANIN SKELETON FROM A METHYL 3,3,3-TRIFLUOROPYRUVATE 2-AMINOBENZYLAMINE ADDUCT

Dolensky B.; Paleta O.; Cejka J.; Ondracek J.; Kvicala J.

首页> 外文期刊>Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry >PREPARATION OF NEW TRIFLUOROMETHYL SUBSTITUTED TRI- AND TETRACYCLIC HETEROCYCLES WITH PEGANIN SKELETON FROM A METHYL 3,3,3-TRIFLUOROPYRUVATE 2-AMINOBENZYLAMINE ADDUCT

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PREPARATION OF NEW TRIFLUOROMETHYL SUBSTITUTED TRI- AND TETRACYCLIC HETEROCYCLES WITH PEGANIN SKELETON FROM A METHYL 3,3,3-TRIFLUOROPYRUVATE 2-AMINOBENZYLAMINE ADDUCT

机译：由3,3,3-三氟丙酮酸2-氨基苯甲酰胺衍生物制备的带有PEGANIN骨架的新的三氟甲基取代的三环和四环杂环

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Addition of 2-aminobenzylamine to methyl trifluoropyruvate afforded methyl 2-((2-aminobenzyl)amino) -3.3,3-trifluoro-2-hydroxypropionate, which reacted with various ketones to give new fluorinated tricyclic and tetracyclic heterocycles with the skeleton of the alkaloid Peganin. Copyright (C) 1996 Elsevier Science Ltd [References: 11]

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《Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry》 |1996年第38期|共4页
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Dolensky B.; Paleta O.; Cejka J.; Ondracek J.; Kvicala J.;
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正文语种 eng
中图分类有机化学;
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Synthase;

机译：合酶;

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1. PREPARATION OF NEW TRIFLUOROMETHYL SUBSTITUTED TRI- AND TETRACYCLIC HETEROCYCLES WITH PEGANIN SKELETON FROM A METHYL 3,3,3-TRIFLUOROPYRUVATE 2-AMINOBENZYLAMINE ADDUCT [J] . Dolensky B., Paleta O., Cejka J., Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 1996,第38期

机译：由3,3,3-三氟丙酮酸2-氨基苯甲酰胺衍生物制备的带有PEGANIN骨架的新的三氟甲基取代的三环和四环杂环
2. Fluorinated butanolides and butenolides part 9. synthesis of 2-(trifluoromethyl)butan-4-olides by wittig reaction using methyl 3,3,3-trifluoropyruvate [J] . Jiri Palecek, Jaroslav Kvicala, Oldrich Palet Journal of Fluorine Chemistry . 2002,第2期

机译：氟化丁醇化物和丁烯内酯第9部分。使用3,3,3-三氟丙酮酸甲酯通过wittig反应合成2-（三氟甲基）丁烷-4-油化物
3. Reactivity of some substituted 5-methyl[1,2,4]triazolo[3,4-b]benzothiazoles and preparation of a new tetracyclic heterocycle 5-methyl-2-phenylpyrrolo[1',2';1,5][1,2,4]triazolo [3,4-b]benzothiazole [J] . Manisha V Deshmukh Indian Journal of Chemistry, Section B. Organic Including Medicinal . 1998,第9期

机译：一些取代的5-甲基[1,2,4]三唑[3,4-b]苯并噻唑的反应性和新的四环杂环5-甲基-2-苯基吡咯并[1'，2'; 1,5] [1]的制备，2,4]三唑[3,4-b]苯并噻唑
4. Synthetic Methods for the Preparation of Ring-FIuorinated Heterocycles via Intramolecular Vinylic Substitution of gewi-Difluoroalkenes [C] . Junji Ichikawa American Chemical Society Symposium on Fluorine-Containing Synthons . 2005

机译：通过石灰 - 二氟烯烃的分子内乙烯基取代制备环丝杂环的合成方法
5. Part I. Hz166, a novel γ-aminobutyric acid (A) receptor subtype-selective ligand active against neuropathic pain Part II. The first enantiospecific, stereospecific total synthesis of the C-19 methyl substituted sarpagine indole alkaloids 19(S), 20(R), 19-(S),20(R)dihydroperaksine-17-al and peraksine Part III. Application of metal-carbenoid chemistry and Brönsted acid mediated cyclization of enaminones for the rapid and efficient access to the tetracyclic (ABCE) skeleton of the Strychnos alkaloids contained in bisindole alkaloids [D] . Edwankar, Rahul V. 2010

机译：第I部分：Hz166，一种新型的对神经性疼痛有活性的γ-氨基丁酸（A）受体亚型选择性配体。 C-19甲基取代的沙雷帕金吲哚生物碱19（S），20（R），19-（S），20（R）dihydroperaksine-17-al和peraksine第三部分的第一个对映体特异性，立体定向全合成。金属类固醇化学和布朗斯台德酸介导的烯胺酮环化的应用，用于快速有效地获取双吲哚生物碱中马兜铃生物碱的四环（ABCE）骨架
6. Substitutional disorder in the ionic diorganoantimony halide adduct bromido/chlorido(0.33/0.67)2-(dimethylaminomethyl)phenyl2-(dimethylammoniomethyl)phenylantimony(III) 0.75-bromide 0.25-chloride [O] . Albert P. Soran, Vilma R. Bojan 2010

机译：离子二有机锑卤化物加合物溴代/氯代（0.33 / 0.67） 2-（二甲基氨基基甲基）苯基 2-（二甲基氨基基甲基）苯基基锑（III）0.75-溴化物0.25-氯离子
7. Chiral brønsted acid catalysts. Activation of methyl 3,3,3-trifluoropyruvate by hydroxymethylpyridine-containing half-sandwich complexes [O] . Carmona Daniel, Lamata M. Pilar, Sánchez Antonio, 2015

机译：手性布朗斯台德酸催化剂。含羟甲基吡啶的半三明治复合物活化3,3,3-三氟丙酮酸甲酯
8. Developmental Toxicity Screening Study in Rats with 1-(Halosubstituted heteromonocycle-methyl) -3-(halosubstituted carbomonocycle)-2- substituted-4-substituted heterocycle. [R] . 2010

机译：用1-（卤代取代的异单环 - 甲基）-3-（卤代取代的碳单环）-2-取代-4-取代的杂环的大鼠的发育毒性筛选研究。

PREPARATION OF NEW TRIFLUOROMETHYL SUBSTITUTED TRI- AND TETRACYCLIC HETEROCYCLES WITH PEGANIN SKELETON FROM A METHYL 3,3,3-TRIFLUOROPYRUVATE 2-AMINOBENZYLAMINE ADDUCT

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