Cervical inflammatory cytokines and other markers in cervical mucus of pregnant women with bacterial vaginosis

摘要

There is little debate that chorioamnionitis (CAM) results in preterm delivery from an ascending infection caused by bacterial vaginosis and cervicitis, both thought to occur before CAM. Many other studies have already demonstrated that lower genital-tract inflammation and infection are risk factors for preterm delivery. In this study, we determined concentrations of interleukin-6 (IL-6), interleukin-8 (IL-8), lactoferrin (LF), and alpha-defencine (a-DF) in cervical' mucus of pregnant women and analyzed their relation to bacterial vaginosis.