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Genomic Testing in Oncology to Improve Clinical Outcomes While Optimizing Utilization: the Evolution of Diagnostic Testing

机译:肿瘤学中的基因组测试可在优化利用率的同时改善临床疗效:诊断测试的发展

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摘要

Cancer care is costly, particularly when chemotherapy and its supportive costs are considered. Yet, chemotherapy is not the right course for every patient. Patients with cancer need appropriate treatment that will give them the best possible outcome. Personalized medicine has become an important area of oncology. In addition to genetic testing, genomic testing has become a useful tool in diagnostics. For genomic assays to be viable, they must have clinical validity, analytic validity, and clinical utility. Stakeholders are willing to provide coverage for such testing through medical policy when there is strong evidence the tests are effective. Genomic testing can be used in decision making to rule out chemotherapy or other treatment options that would not be effective for the care of an individual patient. The use of genomic testing to help eliminate ineffective or possible harmful treatment options and determine appropriate care will benefit the patient while reducing healthcare utilization and costs.
机译:癌症护理费用昂贵,尤其是在考虑化学疗法及其支持费用时。然而,化学疗法并非适合每位患者。癌症患者需要适当的治疗,以使他们获得最佳可能的结果。个性化医学已成为肿瘤学的重要领域。除基因测试外,基因组测试已成为诊断中的有用工具。为了使基因组测定可行,它们必须具有临床有效性,分析有效性和临床实用性。当有力的证据证明测试有效时,利益相关者愿意通过医疗政策为此类测试提供保障。基因组测试可用于决策,以排除对个体患者的护理无效的化学疗法或其他治疗方案。使用基因组测试来帮助消除无效或可能有害的治疗选择并确定适当的护理,将使患者受益,同时降低医疗保健利用率和成本。

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