Effect of Surfactants on Hydrolysis of Mono-N-ethyl-o-toluidine Phosphate

摘要

Hydrolysis of phosphate ester (Mono-N-ethyl-o-toluidine phosphate) in the presence of different surfactants has been studied at 303 K. The rate of reaction has been found to be first-order and fractional order kinetics with respect to [substrate] and [HCl] respectively. The cationic micelles of cetyltrimethylammonium bromide (CTAB), anionic micelles of sodium dodecyl sulfate (SDS) and nonionic micelles of Brij-35 enhanced the rate of reaction to a maximum value and thereafter, the increase in concentration of surfactant decreased the reaction rate. The rate of reaction increased with increase of dielectric constant of the medium. The variation in the rate of hydrolysis by micelles was treated by considering the Menger-Portnoy, Piszkiewicz's and Berezin kinetic models. The various thermodynamic parameters have also been evaluated. The added salts viz KCl, KNO3, K2SO4 enhanced the rate of reaction in the presence of cationic, anionic and non-ionic micelles. The kinetic parameters i.e. micellar phase (k(Psi)) and binding constant (K-S) were determined from the rate (surfactant) profile.