What is the most efficient biopsy regimen for detecting early prostate cancer?

摘要

Parasagittal sextant biopsy guided by trans-rectal ultrasound (TRUS) is the standard method of diagnosing prostate cancer in its early stages. But evidence indicates that this test fails to detect a significant proportion of cancers, leading many physicians to wonder what the optimal biopsy protocol might be. Increasing the number of tissue cores, specifically from the lateral aspect of the prostate, has been shown to enhance detection rate. Is it time to modify the standard prostate biopsy regimen?