Effect of Radiation-Associated Second Malignancies on Prostate Cancer Survival

摘要

In the prostate-specific antigen era, patients with prostate cancer are diagnosed at a younger age and earlier disease stage, and they live longer. Most patients undergo surgery or radiotherapy (RT) and are either cured or outlive their disease. In fact, among >10 000 patients treated by surgery, only 2% actually died of prostate cancer, and a 15-year nomogram predicted a 4% prostate cancer-specific mortality rate at 10 years. Low mortality from prostate cancer is also observed after RT at 10 years of follow-up. Radiotherapy, however, does not cure more patients than surgery