Current Challenges in the Management of Hypothyroidism

摘要

Hypothyroidism, like many chronic conditions, is associated with long-term morbidity that can be minimized through careful management. Primary thyroid failure is a continuous progression from a relatively symptom-free stage into overt disease in which abnormal levels of thyroid hormones are accompanied by troubling symptoms, cognitive impairment, and a heightened risk of cardiovascular morbidity. There is ongoing debate over what constitutes "normal" levels of thyroid hormones. As a result, researchers are exploring the risks posed by subclinical, asymptomatic disease, with the goal of clarifying the indications for treatment.