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The World Post STICH: Is This a 'Game Changer?' A Surgeon's Perspective - Revascularization Is Still the Treatment of Choice

机译:《世界邮报》(STEC):这是“游戏规则改变者”吗?外科医生的观点-血运重建仍然是治疗的选择

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The Surgical Treatment for Ischemic Heart Failure (STICH) trial addressed the broader role of surgical revascularization in patients with heart failure due to reduced LV systolic function EF ≤. 35% and less severe CAD. The primary outcome (all-cause death) was not reduced by CABG. CABG did, however, reduce the secondary outcomes of cardiovascular death (RRR 19%) and death from any cause or cardiovascular hospitalization (RRR 26%).However, 40% of patients enrolled were asymptomatic, and only 49% of patients underwent careful functional evaluation pre-randomization. Moreover, this assessment was for viability, and not ischemia. Careful scrutiny of these trial results illustrates important emerging trends in revascularization, namely the functional as well as anatomic assessment of patients prior to intervention with CABG, and the benefits of CABG in these patients.These STICH findings illustrate the importance of these evaluations in all candidates for revascularization in ischemic heart disease; the results of the trial in terms of the efficacy of CABG need to be interpreted in this light.
机译:缺血性心力衰竭的手术治疗(STICH)试验解决了由于左室收缩功能EF≤降低而导致的心力衰竭患者的外科血运重建的更广泛作用。 35%或更严重的CAD。 CABG并未降低主要结果(全因死亡)。然而,CABG确实减少了心血管死亡(RRR 19%)和因任何原因或心血管住院导致的死亡(RRR 26%)的次要结局,但是40%的患者是无症状的,只有49%的患者接受了仔细的功能检查评估前随机化。此外,该评估是为了生存,而不是缺血。对这些试验结果的仔细审查说明了血运重建的重要新趋势,即在对CABG进行干预之前对患者进行功能和解剖评估,以及CABG对这些患者的益处。用于缺血性心脏病的血运重建;因此,必须从CABG疗效的角度来解释试验结果。

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