Atovaquone + proguanil: new indication. For children weighing as little as 5 kg; an inconvenient form. A flavoured syrup would be better suited to infants and young children.

摘要

The atovaquone plus proguanil combination is an alternative to meflo-quine and quinine for the treatment of uncomplicated malaria in adults and children over 40 kg (about 12 years of age), especially when it is acquired In regions with chloroquine-resistant Plasmodium falciparum (1).The same combination is also marketed in France (GlaxoSmlth-Kline) at a lower dose for malaria prevention In children over 11 kg (2).