Prim?re Immunthrombozytopenie des Erwachsenen – Diagnostik und Therapie, Konsensus-Statement der ?sterreichischen Gesellschaft für H?matologie und Onkologie (?GHO)

摘要

Immune Thrombocytopenia (ITP) is a rare and – in most patients – mild disease, but might be associated with severe or even life-threatening bleeding complications. The treatment of ITP has partly changed in recent years, due to new therapeutic options. International guidelines changed accordingly. This consensus statement by the Austrian Society of Hematology and Oncology (OEGHO) is not a new evaluation of the current evidence, but rather tries to discuss the available international guidelines and adapt them to the situation in Austria. The subject is primary ITP in adults only. Classification, epidemiology, clinical presentation and diagnostics of ITP, and especially the management of this disease, are discussed in detail. This includes current aspects of first, second, and third line therapies, splenectomy with its indications and contraindications, and the use of new therapeutic options like thrombopoetin receptor agonists (TRA).