Finding and using hyperthermophilic enzymes

摘要

Recent developments have enhanced the prospects for the discovery of hyeprthermophilic enzymes has yet to be revealed, and so the intrinsic basis underlying the extraordinary thrmostability of hyperthermophilic enzymes has yet to b revealed, and so engineering this characteristic into less thermophilic enzymes is not possible at the time. Successful efforts to clone and express the genes encoding hyperthermophilic enzymes in mesophilic hosts have improved the availability of high- temperature biocatalysts. The remaining task is the identification of opportunities to make strategic use of the thermoactiv- ity and thermostability of hyperthermophilic enzymes.