Steve eisman knew thatrncalamity would eventually come. The hedge-fund manager bet big against the subprime-mortgage market and won. So did Mike Burry, a social recluse who began investing at night during his medical residency. Jamie Mai and Charlie Ledley, two 30-somethings who started trading in a Berkeley garage, "assumed that there was some grownup in charge of the financial system." There wasn't.
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