1,3,4-THIADIAZOLE DERIVATIVES. PART 5: HETEROPOLYNUCLEAR COMPLEXES OF 2-AMINO-5-MERCAPTO-1,3,4-THIADIAZOLE

摘要

Four new complexes with formula [CuML(AcO)_3]_2, where M = Mn(II); Co(II); Ni(II) and Zn(II), and LH = 2-amino-5-mercapto-1,3,4-thiadiazole, were obtained and characterized by elemental analysis, IR-, EPR- and electronic spectroscopy, as well as magnetic measurements. The reported compounds, which probably are polynuclear species, showed in vitro inhibitory activity towards carbonic anhydrase.