Synthesis of a Quaternary Ammonium Derivative of Chitosan and Its Application to a Cotton Antimicrobial Finish

摘要

A quaternary ammonium derivative of chitosan, N-(2-hydroxy) propyl-3-trimethy- lammonium chitosan chloride (HTCC), is synthesized as an antimicrobial finish for cotton using a reaction of glycidyltrimethylammonium chloride (GTMAC) and chitosan. Results indicate that the degree of substitution (DS) in HTCC calculated by chloride content is a function of the reaction temperature and mole ratio of GTMAC and NH_2 in chitosan. Excess amounts of GTMAC are generally needed to obtain a water-soluble fraction of HTCC.