SCIENTIFIC ETHICS: EMPHASIZING REGULATORY SCIENCE REQUIREMENTS

摘要

This article attempts to provide ethical requirements derived from best available science concept (BAS) and metrics for evaluation of scientific claims (MESC) derived from BAS. The article reviews the historical events leading to the development of ethical requirements for the medical profession. It uses the example of the Tuskegee experiments to demonstrate the lack of ethics in performing human experiments. It briefly describes the Nuremberg trials and ethical codes developed during those trials. Subsequently, medical and other professional ethics are reviewed to indicate the current status of various professions. Another ethical problem briefly addressed in this article deals with personal, including professional, ethics as compared to legal and other requirements. A brief description of BAS principles is followed by identification of MESC pillars. The article describes several ethical principles derived from BAS principles, notably the transparency principle and reproducibility principle. Similarly, the article describes ethical principles derived from the standardization of science pillar addressing the level of maturity of science and the pillar dealing with areas outside the purview of science.