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Markov regression models for count time series with excess zeros: A partial likelihood approach

机译:带有零的计数时间序列的马尔可夫回归模型:部分似然法

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摘要

Count data with excess zeros are common in many biomedical and public health applications. The zero-inflated Poisson (ZIP) regression model has been widely used in practice to analyze such data. In this paper, we extend the classical ZIP regression framework to model count time series with excess zeros. A Markov regression model is presented and developed, and the partial likelihood is employed for statistical inference. Partial likelihood inference has been successfully applied in modeling time series where the conditional distribution of the response lies within the exponential family. Extending this approach to ZIP time series poses methodological and theoretical challenges, since the ZIP distribution is a mixture and therefore lies outside the exponential family. In the partial likelihood framework, we develop an EM algorithm to compute the maximum partial likelihood estimator (MPLE). We establish the asymptotic theory of the MPLE under mild regularity conditions and investigate its finite sample behavior in a simulation study. The performances of different partial-likelihood based model selection criteria are compared in the presence of model misspecification. Finally, we present an epidemiological application to illustrate the proposed methodology.
机译:在许多生物医学和公共卫生应用中,计数多余零的数据很常见。零膨胀泊松(ZIP)回归模型已在实践中广泛用于分析此类数据。在本文中,我们将经典的ZIP回归框架扩展为对具有多余零的时间序列进行建模。提出并建立了马尔可夫回归模型,并将部分似然率用于统计推断。部分似然推理已成功地应用于建模时间序列,其中响应的条件分布位于指数族内。将这种方法扩展到ZIP时间序列会带来方法和理论上的挑战,因为ZIP分布是混合的,因此不在指数族之内。在偏似然框架下,我们开发了一种EM算法来计算最大偏似然估计器(MPLE)。我们建立了在中等规律性条件下的MPLE渐近理论,并在仿真研究中研究了其有限样本行为。在存在模型错误指定的情况下,比较了基于不同部分可能性的模型选择标准的性能。最后,我们提出一种流行病学应用程序来说明所提出的方法。

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