Highly Multiplexed Proteomics from IsoPlexis® is Accelerating Insights from Infectious Diseases to Cancer Immunology

摘要

Understanding immune interactions are critical when it comes to immunotherapies for all types of diseases. Immune interaction is driven by the way cells communicate with each other. Immune cells use cytokines and chemokines to communicate within the immune system. Either as part of normal cellular function, or when challenged, immune cells release cytokines and chemokines which influence cell proliferation, migration, identity, and more; however, "modeling an immunological process can be challenging because the process may...contain multiple cell types, and use multiple cytokines."1 One critical step in understanding this cell communication, and thereby better understanding immune interaction is by identifying the cytokines secreted by the immune cells. To help address this integral challenge, IsoPlexis' technology offers powerful, accessible, high-throughput functional proteomics to help identify the functional mechanisms and drivers of cancer and infectious diseases.