Some of the dramatic neurological problems of Rett syndrome can be reversed in an experimental mouse model, researchers have found. Although the work does not have direct therapeutic applications, scientists studying the devastating genetic disorder hail the findings as a sign that treatments are at least possible in principle. "This is very exciting," says Huda Zoghbi, a geneticist at Baylor College of Medicine in Houston, Texas. "It gives us researchers and the families and patients hope that, as we uncover [biochemical] pathways that could be safely manipulated, we can recover some function in these girls."
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