A New Direction for Gene Loops

摘要

The textbook illustration of a gene depicts a linear structure, with flanking regulatory sequences-a promoter on the left and a terminator on the right, to start and stop transcription, respectively. However, recent analyses of chroma-tin architecture have revealed that the promoter and terminator elements are not necessarily separate in three-dimensional space, but can be juxtaposed to form "gene loops" (1,2).