Response to Comment on 'Dynamics of Dpp Signaling and Proliferation Control'

摘要

Schwank et al. challenge the temporal growth model with an experiment in which Dpp signal transduction is abrogated. They claim that in this condition, cellular Dpp signaling levels do not increase over time but that cells do grow normally. We repeated this experiment and observed an increase of signaling over time. The results are consistent with a temporal model of growth control.