Structural Biology Scales Down

摘要

Three Years Ago, Andrzej Joachimiak decided to take on the superbugs. Infections from these antibiotic-resistant microbes are on an alarming rise globally, accounting for 2 million cases and 23,000 deaths a year in the United States alone. Among the most dangerous bugs are new strains with a protein known as NDM-1 that chops up a wide variety of previously effective antibiotics known asβ-lactams, drugs that include penicillin.