The Toxic Effects Of D.d.t. On Albino Rats

摘要

DDT is an organochlorine pesticide which acts as a poison to a wide variety of insects and mites on contact. The rats were administered with dose of 5 mg/kg body weight/day and 10 mg/kg body weight/day of DDT for 7 and 15 days. Different biochemical parameters like LDH, GOT, GPT and Bilirubin were significantly increased. This shows that the pesticide cause considerable damage to liver even if it is taken for a short duration and in very low quantity. A significant decrease in sugar, proteins, Alkaline phosphatase and acid phosphatase was observed. The insignificant variation in creatinin shows that this pesticide has not caused any damage to the renal tissue.