SYNTHESIS AND CHARACTERIZATION OF 2, 6, 7-TRIARYL-6, 7-DIHYDRO-l, 3, 4-THIADIAZOLO [3, 2-A]-S-TRIAZINE 5-THIONES AS FUNGICIDES

摘要

Twelve title compounds 2, 6, 7-triaryl 6, 7-dihydro-1, 3, 4-thiadiazolo [3, 2-a]-s-triazine 5-thiones [IVa-/] have been synthesized from their requisite 2-arylidine amino-5-aryl-1, 3, 4-thiadiazoles (llla-d) which were prepared from corresponding 2-amino-5-aryl 1, 3, 4-thiadiazoles (lla-b). These starting material 2-amino-5aryl-1, 3, 5-thiadiazoles were obtained from their corresponding aroyl thiosemi carbazides [Ia-b]. All the synthesized compounds [IVa-/| were characterized by their molecular formula, elemental analysis I.R. and HNMR spectral data. Fungicidal activity of the synthesized compounds was evaluated against Phytophthora infestans and Aspergillus niger. Fungicidal screening data correlated with the structural features of the tested compounds.