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Insight Into Neurocognitive Dysfunction in Schizophrenia

机译:精神分裂症的神经认知功能障碍的见解。

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摘要

Insight into psychotic symptoms is typically poor in schizophrenia; however, it is not known whether insight into neurocognitive impairment is similarly impaired. Most people with schizophrenia experience cognitive dysfunction, and the deficits in attention, memory, and critical thinking have been associated with poor functional outcome. As new treatments are developed for the cognitive impairments, it will be important to know whether patients will be receptive to yet another therapy. Insight is an important factor in treatment compliance and treatment outcome; however, it is not known if patients have insight into their cognitive dysfunction. In order to assess insight into neuro cognitive dysfunction, 75 subjects were administered the Measure of Insight into Cognition–Clinician Rated, a newly created measure based on the Scale to Access the Unawareness of Mental Disorder, that assesses insight into cognitive impairment. Subjects were also administered the Brief Assessment of Cognition in Schizophrenia and Independent Living Scale–Problem Solving to objectively assess neuropsychological status and problem-solving skills needed for independent living. Results demonstrated that virtually all subjects had cognitive impairment, yet insight into their neuro cognitive symptoms was limited. This finding has potential implications for treatment programs seeking to improve cognitive functioning in schizophrenia
机译:对精神病症状的洞察力通常在精神分裂症中较差;然而,尚不清楚对神经认知障碍的见识是否同样受到损害。大多数精神分裂症患者会出现认知功能障碍,注意力,记忆力和批判性思维的缺陷与不良的功能预后有关。随着针对认知障碍的新疗法的发展,了解患者是否会接受另一种疗法将至关重要。洞察力是治疗依从性和治疗结果的重要因素;然而,尚不清楚患者是否对他们的认知功能障碍有见识。为了评估对神经认知功能障碍的洞察力,对75名受试者进行了“知觉-临床医生评定洞察力”评估,这是一种基于访问精神障碍无意识量表的新方法,用于评估对认知障碍的洞察力。还对受试者进行了“精神分裂症认知的简短评估”和“独立生活量表-问题解决”,以客观评估独立生活所需的神经心理状态和解决问题的技能。结果表明,几乎所有受试者都有认知障碍,但对他们的神经认知症状的了解有限。这一发现对寻求改善精神分裂症认知功能的治疗计划具有潜在的影响。

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  • 来源
    《Schizophrenia Bulletin》 |2008年第6期|1221-1230|共10页
  • 作者单位

    Department of Psychiatry Columbia University Medical Center 180 Fort Washington Avenue HP234 New York NY 10467;

    Department of Psychiatry University of Pennsylvania Philadelphia PA;

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  • 正文语种 eng
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