Apparatus for forming fully coated particles with a solid core

摘要

This invention relates to a reactor for forming fully coated particles having a solid core, a method of forming such fully coated particles and to a plurality of fully coated particles.The invention also relates to a pharmaceutical composition comprising a pharmacologically-effective amount of a biologically active agent in the form of such fully coated particles and to a pharmaceutical or veterinary formulation comprising such a pharmaceutical composition.It is known to apply a coating to a substance using a gas phase coating technique, such as atomic layer deposition (ALD).The gas phase coating technique sequentially introduces pulses of gas phase materials or reactants to deposit or form a coating on the substance.In many gas phase coating techniques, it is pulses of precursor gases that are sequentially introduced.The precursor gases react with each other on the surface of the substance, thus "growing" a coating onto the substance.Several pulses of gas phase materials can be applied to form a coating of a desired thickness and composition.