Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) and its metabolic precursor, gamma-butyrolactone (GBL) in rats

Lisa E. Baker; Timothy J. Van Tilburg; Andrew E. Brandt; Alan Poling

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Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) and its metabolic precursor, gamma-butyrolactone (GBL) in rats

机译：γ-羟基丁酸酯（GHB）及其代谢前体γ-丁内酯（GBL）对大鼠的歧视性刺激作用

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摘要

Gamma-hydroxybutyrate (GHB) is becoming an increasingly popular drug of abuse. Metabolic precursors of GHB, gamma-butyrolactone (GBL) and 1,4-butanediol (BDL), are commercially available industrial solvents that may also present potential health risks. Relatively little is known about the neurobehavioral effects of GHB and its precursors.

机译：γ-羟基丁酸酯（GHB）正成为一种越来越流行的滥用药物。 GHB的代谢前体，γ-丁内酯（GBL）和1,4-丁二醇（BDL）是可商购的工业溶剂，也可能存在潜在的健康风险。关于GHB及其前体的神经行为影响知之甚少。

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来源
《Psychopharmacology》 |2005年第3期|458-466|共9页
作者
Lisa E. Baker; Timothy J. Van Tilburg; Andrew E. Brandt; Alan Poling;
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作者单位

Department of Psychology Western Michigan University;

Department of Psychology Western Michigan University;

Department of Psychology Western Michigan University;

Department of Psychology Western Michigan University;

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原文格式 PDF
正文语种 eng
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关键词
GHB; GBL; BDL; Benzodiazepines; NMDA antagonists; Ethanol; NCS-382; CGP-35348; Drug discrimination; Rats;

机译：GHB;GBL;BDL;苯二氮卓类药物;NMDA拮抗剂;乙醇;NCS-382;CGP-35348;药物鉴别;大鼠;

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1. Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) and its metabolic precursor, gamma-butyrolactone (GBL) in rats. [J] . Baker LE, Van Tilburg TJ, Brandt AE, Psychopharmacology . 2005,第3期

机译：γ-羟基丁酸酯（GHB）及其代谢前体γ-丁内酯（GBL）在大鼠中的歧视性刺激作用。
2. Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons. [J] . Goodwin AK, Brown PR, Jansen EE, Psychopharmacology . 2009,第3期

机译：狒狒中γ-羟基丁酸酯（GHB）前体γ-丁内酯（GBL）和1,4-丁二醇（1,4-BD）的行为效应和药代动力学。
3. Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons [J] . A. K. Goodwin, P. R. Brown, E. E. W. Jansen, Psychopharmacology . 2009,第3期

机译：狒狒中γ-羟基丁酸酯（GHB）前体γ-丁内酯（GBL）和1,4-丁二醇（1,4-BD）的行为效应和药代动力学
4. Enumerating Precursor Sets of Target Metabolites in a Metabolic Network [C] . L. Cottret, P.V. Milreu, V. Acuna, Algorithms in Bioinformatics . 2008

机译：枚举代谢网络中目标代谢物的前体集
5. Analysis of gamma-hydroxybutyrate (GHB) in beverages. [D] . Tschaekofske, Scott James. 2000

机译：饮料中γ-羟基丁酸酯（GHB）的分析。
6. Behavioral effects and pharmacokinetics of gamma-hydroxybutyrate (GHB) precursors gamma-butyrolactone (GBL) and 14-butanediol (14-BD) in baboons [O] . A. K. Goodwin, P. R. Brown, E. E. W. Jansen, -1

机译：狒狒中γ-羟基丁酸酯（GHB）前体γ-丁内酯（GBL）和14-丁二醇（14-BD）的行为效应和药代动力学
7. Medical and legal confusion surrounding gamma-hydroxybutyrate (GHB) and its precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4BD) [O] . D.M. Wood, C. Warren-Gash, T. Ashraf, 2007

机译：γ-羟基丁酸盐（GHB）及其前体γ-丁内酯（GBL）和1,4-丁二醇（1,4bd）的医疗和法律混乱

Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) and its metabolic precursor, gamma-butyrolactone (GBL) in rats

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