Offspring of parents with an alcohol use disorder prefer higher levels of brain alcohol exposure in experiments involving computer-assisted self-infusion of ethanol (CASE)

Ulrich S. Zimmermann; Inge Mick; Manfred Laucht; Victor Vitvitskiy; Martin H. Plawecki; Karl F. Mann; Sean O’Connor

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Offspring of parents with an alcohol use disorder prefer higher levels of brain alcohol exposure in experiments involving computer-assisted self-infusion of ethanol (CASE)

机译：在涉及计算机辅助自我酒精注入（CASE）的实验中，患有酒精使用障碍的父母的后代更喜欢较高水平的大脑酒精暴露

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Rationale Acute alcohol effects may differ in social drinkers with a positive family history of alcohol use disorders (FHP) compared to FH negative (FHN) controls.

机译：基本原理与具有FH阴性（FHN）对照的饮酒家族史阳性（FHP）的社会饮酒者相比，急性饮酒可能会有所不同。

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来源
《Psychopharmacology》 |2009年第4期|p.689-697|共9页
作者
Ulrich S. Zimmermann; Inge Mick; Manfred Laucht; Victor Vitvitskiy; Martin H. Plawecki; Karl F. Mann; Sean O’Connor;
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正文语种 eng
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关键词
Alcoholism; Ethanol; Self; administration; Genetic risk; Sensitivity; Tolerance; Freibier; CASE;

机译：酗酒;乙醇;自我管理遗传风险;灵敏度;公差;弗雷比耶;案件;

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1. Offspring of parents with an alcohol use disorder prefer higher levels of brain alcohol exposure in experiments involving computer-assisted self-infusion of ethanol (CASE). [J] . Zimmermann US, Mick I, Laucht M, Psychopharmacology . 2009,第4期

机译：在涉及计算机辅助乙醇自我灌输（CASE）的实验中，患有酒精使用障碍的父母的后代更喜欢较高水平的大脑酒精暴露。
2. Development and pilot validation of computer-assisted self-infusion of ethanol (CASE): a new method to study alcohol self-administration in humans. [J] . Zimmermann US, Mick I, Vitvitskyi V, Alcoholism: Clinical and experimental research . 2008,第7期

机译：计算机辅助乙醇自我输注（CASE）的开发和先导验证：研究人类酒精自我给药的一种新方法。
3. Effects of Ethanol Exposure on Subsequent Acquisition and Extinction of Ethanol Self-Administration and Expression of Alcohol-Seeking Behavior in Adult Alcohol-Preferring (P) Rats: II. Adult Exposure. [J] . Rodd Henricks ZA, Bell RL, Kuc KA, Alcoholism: Clinical and experimental research . 2002,第11期

机译：乙醇暴露对成年酒精偏爱（P）大鼠的酒精自服和饮酒行为表达的随后吸收和消灭的影响：II。成人接触。
4. Metabolomic Profiling of Brain Tissue Extracts from Alcohol Preferring and Non-Preferring Rats; Toward Identification of Alcoholism Biomarkers [C] . Yehia Mechref, Jason Starkey, Ali Kettani, ASMS Conference on Mass Spectrometry and Allied Topics . 2006

机译：脑组织从酒精偏好和非偏爱大鼠提取的代谢组分谱;探讨酗酒生物标志物
5. Peri-adolescent alcohol consumption enhances the reinforcing and stimulatory properties of ethanol within the adult mesolimbic dopamine system in alcohol preferring P rats [D] . Toalston, Jamie E. 2011

机译：青少年期饮酒可增强嗜酒精性P大鼠的成年中肢边缘多巴胺系统中乙醇的增强和刺激特性。
6. Effects of Lifelong Ethanol Consumption on Brain Monoamine Transmitters in Alcohol-Preferring Alko Alcohol (AA) Rats [O] . Pia Jaatinen, Maija Sarviharju, Noora Raivio, 2013

机译：终生乙醇消耗对酒精偏爱的醇（AA）大鼠脑单胺递质的影响
7. Paternal alcohol exposure in mice alters brain NGF and BDNF and increases ethanol-elicited preference in male offspring [O] . Ceccanti, Mauro, Coccurello, Roberto, Carito, Valentina, 2016

机译：小鼠暴露于父亲的酒精会改变大脑NGF和BDNF并增加乙醇对雄性后代的偏好

Offspring of parents with an alcohol use disorder prefer higher levels of brain alcohol exposure in experiments involving computer-assisted self-infusion of ethanol (CASE)

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