Residual effects of esmirtazapine on actual driving performance: overall findings and an exploratory analysis into the role of CYP2D6 phenotype

Johannes G. Ramaekers; Silke Conen; Pieter Jan de Kam; Sabine Braat; Pierre Peeters; Eef L. Theunissen; Neely Ivgy-may

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Residual effects of esmirtazapine on actual driving performance: overall findings and an exploratory analysis into the role of CYP2D6 phenotype

机译：esmirtazapine对实际驾驶表现的残留影响：整体发现和CYP2D6表型作用的探索性分析

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摘要

Esmirtazapine is evaluated as a novel drug for treatment of insomnia.

机译：依米氮平被评价为治疗失眠的新药。

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来源
《Psychopharmacology》 |2011年第2期|p.321-332|共12页
作者
Johannes G. Ramaekers; Silke Conen; Pieter Jan de Kam; Sabine Braat; Pierre Peeters; Eef L. Theunissen; Neely Ivgy-may;
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作者单位

Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands;

Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands;

MSD, Oss, The Netherlands;

MSD, Oss, The Netherlands;

MSD, Oss, The Netherlands;

Department of Neuropsychology and Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands;

Merck &amp Co., Summit, NJ, USA;

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正文语种 eng
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关键词
Hypnotics; H1 antagonism; Driving; Cognition; CYP2D6 phenotype;

机译：催眠药;H1拮抗作用;驾驶;认知;CYP2D6表型;

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专利

1. Residual effects of esmirtazapine on actual driving performance: overall findings and an exploratory analysis into the role of CYP2D6 phenotype. [J] . Ramaekers JG, Conen S, de Kam PJ, Psychopharmacology . 2011,第2期

机译：esmirtazapine对实际驾驶表现的残留影响：整体发现和对CYP2D6表型作用的探索性分析。
2. Zopiclone's Residual Effects on Actual Driving Performance in a Standardized Test: A Pooled Analysis of Age and Sex Effects in 4 Placebo-Controlled Studies [J] . Leufkens Tim R. M., Vermeeren A. Clinical therapeutics . 2014,第1期

机译：Zopiclone在标准化测试中对实际驾驶性能的剩余影响：4个安慰剂对照研究中的年龄和性别效应的汇总分析
3. Predicting psychopharmacological drug effects on actual driving performance (SDLP) from psychometric tests measuring driving-related skills [J] . VersterJ.C., RothT. Psychopharmacology . 2012,第2期

机译：通过测量驾驶相关技能的心理测验预测心理药物对实际驾驶表现的影响（SDLP）
4. Effects of In-Vehicle Secondary Distraction Tasks on Driving Performance: A Naturalistic Driving Study and Findings [C] . Yanli Ma, Huimin Shi, Luyang Fan COTA international conference of transportation professionals . 2017

机译：车载二次分心任务对驾驶性能的影响：自然驾驶研究和发现
5. The Effects of Driving Automation Systems on Human Driving Performance and Driver Fatigue [D] . Wong, Lily R. 2018

机译：驾驶自动化系统对人类驾驶性能和司机疲劳的影响
6. Residual effects of esmirtazapine on actual driving performance: overall findings and an exploratory analysis into the role of CYP2D6 phenotype [O] . Johannes G. Ramaekers, Silke Conen, Pieter Jan de Kam, -1

机译：esmirtazapine对实际驾驶表现的残留影响：整体发现和CYP2D6表型作用的探索性分析
7. Residual effects of esmirtazapine on actual driving performance: overall findings and an exploratory analysis into the role of CYP2D6 phenotype [O] . Johannes G. Ramaekers, Silke Conen, Pieter Jan de Kam, 2011

机译：esmirtazapine对实际驾驶表现的残留影响：整体发现和CYP2D6表型作用的探索性分析
8. Flurazepam Hcl's Residual (Hangover) Effects Upon Actual Driving Performance [R] . Ohanlon, J. F., Volkerts, E. R., Devries, G., 1984

机译：Flurazepam Hcl对实际驾驶性能的残留（宿醉）影响

Residual effects of esmirtazapine on actual driving performance: overall findings and an exploratory analysis into the role of CYP2D6 phenotype

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