Effects of quetiapine and sertindole on subchronic ketamine-induced deficits in attentional set-shifting in rats

摘要

Prefrontal cortical dysfunctions, including an impaired ability to shift perceptual attentional set, are core features of schizophrenia. Nevertheless, the effectiveness of second-generation antipsychotic drugs in treating specific prefrontal dysfunctions remains equivocal.