In vivo quantification of localized neuronal activation and inhibition in the rat brain using a dedicated high temporal-resolution β~+-sensitive microprobe

摘要

Understanding brain disorders, the neural processes implicated in cognitive functions and their alterations in neurodegenerative pa- thologies, or testing new therapies for these diseases would benefit greatly from combined use of an increasing number of rodent models and neuroimaging methods specifically adapted to the rodent brain. Besides magnetic resonance (MR) imaging and functional MR, positron-emission tomography (PET) remains a unique methodology to study in vivo brain processes.