Redox systems of the cell: Possible links and implications

摘要

Oxidation-reduction status (redox) is an important regulator of various metabolic functions of the cell. Perturba- tions in the redox status of cells by external or internal stimuli elicit distinct responses, resulting in alteration of cell function. Glutathione and thioredoxin are two ma- jor reducing systems of the eukaryotic cell that maintain redox balance, as well as interact with various transducer and ef- fector molecules to bring about specific responses. However, these two systems dif- er greatly in their functions and re- ponses to various types of stress.