Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

Lin Zhang; Stefano Volinia; Tomas Bonome; George Adrian Calin; Joel Greshock et al

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Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

机译：基因组和表观遗传学改变使人类上皮性卵巢癌中的microRNA表达失控

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MicroRNAs (miRNAs) are an abundant class of small noncoding RNAs that function as negative gene regulators. miRNA deregulation is involved in the initiation and progression of human cancer; however, the underlying mechanism and its contributions to genome

机译：MicroRNA（miRNA）是一类丰富的小型非编码RNA，它们起着负基因调节剂的作用。 miRNA的失调与人类癌症的发生和发展有关。但是，其潜在机制及其对基因组的贡献

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《Proceedings of the National Academy of Sciences of the United States of America》 |2008年第19期|7004-7009|共6页
作者
Lin Zhang; Stefano Volinia; Tomas Bonome; George Adrian Calin; Joel Greshock et al;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
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关键词
Dlk1-Gtl2 domain; noncoding RNA;

机译：Dlk1-Gtl2域;非编码RNA;

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专利

1. Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer. [J] . Murphy SK, Huang Z, Wen Y, Molecular cancer research: MCR . 2006,第4期

机译：上皮性卵巢癌中常见的IGF2 / H19域表观遗传学改变和IGF2表达升高。
2. Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer. [J] . Ambs S, Prueitt RL, Yi M, Cancer research: The official organ of the American Association for Cancer Research, Inc . 2008,第15期

机译：microRNA和信使RNA的基因组分析揭示了前列腺癌中microRNA表达失调。
3. Microarray Comparative Genomic Hybridization Profile of a Murine Model for Epithelial Ovarian Cancer Reveals Genomic Imbalances Resembling Human Ovarian Carcinomas. [J] . Munroe DJ Tumour biology : . 2005,第5期

机译：上皮性卵巢癌的鼠模型的微阵列比较基因组杂交概况揭示了类似于人类卵巢癌的基因组失衡。
4. Epigenetic-regulated microRNAs in glioblastoma and ovarian cancers [C] . DAVID AGUSTRIAWAN, YU-LIANG LEE, JIM SHEU, WSEAS International Conference on Environment, Ecosystems and Development . 2013

机译：胶质母细胞瘤和卵巢癌中的表观遗传调节的microRNA
5. Cancer/Germline (CG) antigens and epigenetic deregulation in human epithelial ovarian cancer (EOC). [D] . Woloszynska-Read, Anna. 2009

机译：人类上皮性卵巢癌（EOC）中的癌症/种系（CG）抗原和表观遗传失调。
6. Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer [O] . Lin Zhang, Stefano Volinia, Tomas Bonome, 2008

机译：基因组和表观遗传学改变使人类上皮性卵巢癌中的microRNA表达失控
7. Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer [O] . Zhang, Lin, Volinia, Stefano, Bonome, Tomas, 2008

机译：基因组和表观遗传学改变使人类上皮性卵巢癌中的microRNA表达失控
8. Modeling Human Epithelial Ovarian Cancer in Mice by Alteration of Expression of the Expression of the BRCA1 and/p53 Genes [R] . Connolly, D. C. 2006

机译：通过改变BRCa1和/ p53基因表达对小鼠人卵巢上皮性癌的建模

Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer

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