All change at Holliday junction

摘要

Both of these studies illustrate that the intrinsic structural preferences of the DNA junctions appear to exert a strong influence on the outcome of the recombination reactions, and that an exchange of stacking partners in the junction is a critical event in the proposed mechanism. Although physical studies of the isolated DNA structures may seem oversimplistic in some cases, it is clear that such data can provide important raw material for thinking about biologically important mecha- nisms.