Elastic Bond Network Model for Protein Unfolding Mechanics

Hendrik Dietz; Matthias Rief

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Elastic Bond Network Model for Protein Unfolding Mechanics

机译：蛋白质展开力学的弹性键网络模型

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摘要

Recent advances in single molecule mechanics have made it possible to investigate the mechanical anisotropy of protein stability in great detail. A quantitative prediction of protein unfolding forces at experimental time scales has so far been difficult.

机译：单分子力学的最新进展使得更详细地研究蛋白质稳定性的机械各向异性成为可能。到目前为止，在实验时间尺度上对蛋白质展开力的定量预测一直很困难。

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来源
《Physical review letters》 |2008年第9期|p.300-303|共4页
作者
Hendrik Dietz; Matthias Rief;
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作者单位

Dana-Farber Cancer Institute and BCMP, Harvard Medical School, Boston, Massachusetts 02115, USA;

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原文格式 PDF
正文语种 eng
中图分类物理学;
关键词
mechanical properties; single molecule manipulation of proteins and other biological molecules;

机译：机械性能;蛋白质和其他生物分子的单分子操纵;

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1. Temperature-induced unfolding behavior of proteins studied by tensorial elastic network model [J] . Srivastava Amit, Granek Rony Proteins: Structure, Function, and Genetics . 2016,第12期

机译：张量弹性网络模型研究蛋白质的温度诱导展开行为
2. Tensorial elastic network model for protein dynamics: Integration of the anisotropic network model with bond-bending and twist elasticities [J] . SrivastavaA., HaleviR.B., VekslerA., Proteins: Structure, Function, and Genetics . 2012,第12期

机译：用于蛋白质动力学的张量弹性网络模型：具有键合弯曲和扭转弹性的各向异性网络模型的集成
3. Protein unfolding behavior studied by elastic network model. [J] . Su JG, Li CH, Hao R, Biophysical Journal . 2008,第12期

机译：通过弹性网络模型研究蛋白质的展开行为。
4. FIBRIN NETWORKS SUSTAIN LARGE EXTENSIONS DUE TO UNFOLDING PROTEINS [C] . Prashant K. Purohit First global congress on nanoengineering for medicine and biology 2010 . 2010

机译：由于折叠蛋白的存在，FIBRIN网络可以保持较大的扩展
5. Mechanics of molecular bond clusters between elastic media: Stochastic-elastic coupling in cell-matrix adhesion. [D] . Qian, Jin. 2010

机译：弹性介质之间分子键簇的力学：细胞-基质粘附中的随机-弹性耦合。
6. Protein Unfolding Behavior Studied by Elastic Network Model [O] . Ji Guo Su, Chun Hua Li, Rui Hao, 2008

机译：弹性网络模型研究蛋白质的展开行为
7. Assessing Limitations of Elastic Network Models in Describing Equilibrium Protein Flexibility and Extensions to Predict Non-Equilibrium Unfolding Dynamics of Proteins [O] . Venkatramani Ravindra, Sarkar Ranja, Kotamarthi Hema Chandra, 2014

机译：在描述平衡蛋白质柔韧性和预测蛋白质非平衡展开动力学的扩展中评估弹性网络模型的局限性

Elastic Bond Network Model for Protein Unfolding Mechanics

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