The Utility of p-N-Succinimidobenzoyl Isothiocyanate in Synthesis of Benzoxazole, Quinazoline, Pyrimidine, 1,2,4-Triazoline, 1,3-Thiazolidine, and Thiourea Derivatives

摘要

Reactions of p-N-succinimidobenzoyl isothiocyanate (1) with different nucleophilic reagents afforded adducts. Simultaneous or subsequent cyclization of these adducts gave access to a variety of different heterocycles, including benzoxazole, quinazoline, pyrimidine, 1,2,4-triazoline, 1,3-thiazolidine and others. The structures of the new products were confirmed by their micro-analytical and spectral data.Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.View full textDownload full textKeywordsBenzoxazole, pyrimidine, quinazoline, p-N-succinimidobenzoyl isothiocyanate, thiourea derivatives, 1,2,4-triazolineRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/10426500903127557