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Formulation and In-Vitro and In-Vivo Evaluation of a Mucoadhesive Gel Containing Freeze Dried Black Raspberries: Implications for Oral Cancer Chemoprevention

机译:含冷冻干燥黑莓的粘膜黏着剂的配方,体外和体内评估:口腔癌化学预防的意义

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摘要

The purpose of these studies was to formulate mucoadhesive gels containing freeze dried black raspberries (FBR) and to determine optimum parameters for a subset of FBR bioactive compounds including anthocyanin stability, absorption and penetration in-vitro and in-vivo.
机译:这些研究的目的是配制包含冷冻黑莓(FBR)的粘膜粘附凝胶,并确定FBR生物活性化合物子集的最佳参数,包括花色素苷的稳定性,体外和体内吸收和渗透。

著录项

  • 来源
    《Pharmaceutical Research》 |2007年第4期|728-737|共10页
  • 作者单位

    Department of Oral Maxillofacial Surgery ampamp Pathology College of Dentistry The Ohio State University 305 West 12th Avenue Columbus Ohio 43210-1241 USA;

    The Ohio State University Comprehensive Cancer Center and Solove Research Institute Columbus Ohio USA;

    Department of Oral Maxillofacial Surgery ampamp Pathology College of Dentistry The Ohio State University 305 West 12th Avenue Columbus Ohio 43210-1241 USA;

    Department of Orthodontics College of Dentistry The Ohio State University Columbus Ohio USA;

    Department of Oral Maxillofacial Surgery ampamp Pathology College of Dentistry The Ohio State University 305 West 12th Avenue Columbus Ohio 43210-1241 USA;

    Department of Food Science College of Agriculture The Ohio State University Columbus Ohio USA;

    Department of Food Science College of Agriculture The Ohio State University Columbus Ohio USA;

    Department of Pharmaceutical Sciences College of Pharmacy University of Kentucky Lexington Kentucky USA;

    Department of Pharmaceutical Sciences College of Pharmacy University of Kentucky Lexington Kentucky USA;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    anthocyanins; black raspberries; chemoprevention; local delivery; oral cancer;

    机译:花青素;黑树莓;化学预防;局部给药;口腔癌;

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