Effect of Particle Size and Compression Force on Compaction Behavior and Derived Mathematical Parameters of Compressibility

摘要

To analyze the influence of inherent densification and deformation properties of paracetamol on the mathematical parameters derived from Heckel, Walker, Kawakita, and Adams equations and to correlate these with single particle nominal fracture strength and bulk compression parameters using confined compression on a fully instrumented rotary tablet press.