The Role of Constitutive Androstane Receptor in Oxazaphosphorine-Mediated Induction of Drug-Metabolizing Enzymes in Human Hepatocytes

Duan Wang; Linhao Li; Jennifer Fuhrman; Stephen Ferguson; Hongbing Wang

首页> 外文期刊>Pharmaceutical Research >The Role of Constitutive Androstane Receptor in Oxazaphosphorine-Mediated Induction of Drug-Metabolizing Enzymes in Human Hepatocytes

【24h】

The Role of Constitutive Androstane Receptor in Oxazaphosphorine-Mediated Induction of Drug-Metabolizing Enzymes in Human Hepatocytes

机译：本构雄甾烷受体在氧杂氮磷介导的人肝细胞药物代谢酶诱导中的作用

获取原文

获取原文并翻译 | 示例

获取外文期刊封面目录资料

开具论文收录证明 >>

文献代查 >>

文献数据库（团队版） >>

页面导航

摘要
著录项
引文网络
相似文献
相关主题

摘要

Purpose To investigate the roles of the constitutive androstane receptor (CAR) in cyclophosphamide (CPA)- and ifosfamide (IFO)-mediated induction of hepatic drug-metabolizing enzymes (DME).

机译：目的探讨组成型雄烷受体（CAR）在环磷酰胺（CPA）和异环磷酰胺（IFO）介导的肝药物代谢酶（DME）诱导中的作用。

著录项

来源
《Pharmaceutical Research》 |2011年第8期|p.2034-2044|共11页
作者
Duan Wang; Linhao Li; Jennifer Fuhrman; Stephen Ferguson; Hongbing Wang;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. The role of constitutive androstane receptor in oxazaphosphorine-mediated induction of drug-metabolizing enzymes in human hepatocytes. [J] . Wang D, Li L, Fuhrman J, Pharmaceutical research . 2011,第8期

机译：组成型雄烷受体在氧杂氮磷介导的人肝细胞药物代谢酶诱导中的作用。
2. Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor. [J] . Kohle C, Bock KW Biochemical Pharmacology . 2009,第4期

机译：通过Ah受体，孕烷X受体和组成型雄甾烷受体来协调人类药物代谢酶和共轭转运蛋白的调控。
3. Role of constitutive androstane receptor in toll-like receptor-mediated regulation of gene expression of hepatic drug-metabolizing enzymes and transporters [J] . Shah,P., Guo,T., Moore,D.D., Drug Metabolism and Disposition: The Biological Fate of Chemicals . 2014,第1期

机译：组成型雄甾烷受体在toll样受体介导的肝药物代谢酶和转运蛋白基因表达调控中的作用
4. Direct activation of Constitutive Androstane Receptor by Phthalates [C] . Haishan LI, Wenchao AI, Hui HAN, International Conference on Biological Engineering and Pharmacy . 2017

机译：通过邻苯二甲酸酯直接激活组成型和rostane受体
5. Novel human Constitutive Androstane Receptor Activators and their Effects on Hepatic Energy Homeostasis. [D] . Lynch, Caitlin. 2014

机译：新型人类组成型雄激素受体激活剂及其对肝能量稳态的影响。
6. The Role of Constitutive Androstane Receptor in Oxazaphosphorine-mediated Induction of Drug-metabolizing Enzymes in Human Hepatocytes [O] . Duan Wang, Linhao Li, Jennifer Fuhrman, -1

机译：组成型和rostane受体在人肝细胞中药物代谢介导的诱导的作用
7. The Role of Constitutive Androstane Receptor in Oxazaphosphorine-Mediated Induction of Drug-Metabolizing Enzymes in Human Hepatocytes [O] . Duan Wang, Linhao Li, Jennifer Fuhrman, 2011

机译：组成型和rostane受体在人肝细胞中药物代谢介导的诱导的作用
8. Endosulfan-alpha Induces CYP26 and CYP3A4 by Activating the Pregnane X Receptor But Not the Constitutive Androstane Receptor [R] . Casabar, R. C. 2006

机译：硫丹-α通过激活孕烷X受体而不是组成型雄甾烷受体诱导CYp26和CYp3a4

The Role of Constitutive Androstane Receptor in Oxazaphosphorine-Mediated Induction of Drug-Metabolizing Enzymes in Human Hepatocytes

摘要

著录项

引文网络

相似文献

相关主题

期刊订阅