Measuring Tissue Back-Pressure - In Vivo Injection Forces During Subcutaneous Injection

Andrea Allmendinger; Robert Mueller; Edward Schwarb; Mark Chipperfield; Joerg Huwyler; Hanns-Christian Mahler; Stefan Fischer

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Measuring Tissue Back-Pressure - In Vivo Injection Forces During Subcutaneous Injection

机译：在皮下注射过程中测量组织背压-体内注射力

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Purpose Limited information is available on injection forces of parenterals representing the in vivo situation. Scope of the present study was to investigate the contribution of the subcutaneous (sc) tissue layer to injection forces during in vivo injection.

机译：目的关于肠胃外注射代表体内情况的注射力的信息有限。本研究的范围是研究在体内注射过程中皮下（sc）组织层对注射力的贡献。

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来源
《Pharmaceutical Research 》 |2015年第7期| 2229-2240| 共12页
作者
Andrea Allmendinger; Robert Mueller; Edward Schwarb; Mark Chipperfield; Joerg Huwyler; Hanns-Christian Mahler; Stefan Fischer;
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Late Stage Pharmaceutical and Processing Development Pharmaceutical Development Supplies Pharma Technical Development Biologics EU F. Hoffmann-La Roche Ltd">(1);

Division of Pharmaceutical Technology Department of Pharmaceutical Sciences University of Basel">(2);

Late Stage Pharmaceutical and Processing Development Pharmaceutical Development Supplies Pharma Technical Development Biologics EU F. Hoffmann-La Roche Ltd">(1);

Device Development Pharma Technical Development Biologics EU F. Hoffmann-La Roche Ltd">(3);

Device Development Pharma Technical Development Biologics EU F. Hoffmann-La Roche Ltd">(3);

Division of Pharmaceutical Technology Department of Pharmaceutical Sciences University of Basel">(2);

Late Stage Pharmaceutical and Processing Development Pharmaceutical Development Supplies Pharma Technical Development Biologics EU F. Hoffmann-La Roche Ltd">(1);

Late Stage Pharmaceutical and Processing Development Pharmaceutical Development Supplies Pharma Technical Development Biologics EU F. Hoffmann-La Roche Ltd">(1);

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1. Measuring Tissue Back-Pressure - In Vivo Injection Forces During Subcutaneous Injection [J] . Allmendinger Andrea, Mueller Robert, Schwarb Edward, Pharmaceutical research . 2015 ,第7期

机译：皮下注射期间测量组织背压-体内注射力
2. A Patient Care Program for Adjusting the Autoinjector Needle Depth According to Subcutaneous Tissue Thickness in Patients With Multiple Sclerosis Receiving Subcutaneous Injections of Glatiramer Acetate [J] . Sanchez Masid Maria Luisa, Horno Ocana Rosalia, Diaz Gil Maria Jesus, The Journal of neuroscience nursing: journal of the American Association of Neuroscience Nurses . 2015 ,第1期

机译：接受皮下注射醋酸格拉替雷的多发性硬化症患者，根据皮下组织厚度调节自动注射针深度的患者护理程序
3. Electromechanical method coupling non-invasive skin impedance probing and in vivo subcutaneous liquid microinjection: controlling the diffusion pattern of nanoparticles within living soft tissues [J] . Baeckkyoung Sung, Se Hoon Kim, Jin-Kyu Lee, Biomedical Microdevices . 2014 ,第4期

机译：机电方法结合无创皮肤阻抗探测和体内皮下液体显微注射：控制纳米粒子在活软组织内的扩散模式
4. Long nanowire arrays for in vitro and in vivo DNA injections into cells in brain tissues [C] . Yoshihiro Kubota, Rika Numano, Akihiro Goryu, IEEE Micro Electro Mechanical Systems Conference . 2018

机译：长纳米线阵列，用于在体外和体内将DNA注射到脑组织的细胞中
5. In Vivo Periodical Monitoring of Immune Cell Infiltration in Response to Feathers and Intramuscular Injection of IONPs Using the Pulp (Dermis) of Growing Feathers as Test Site Tissue in Chickens. [D] . Alaamri, Olfat T. 2015

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6. A Patient Care Program for Adjusting the Autoinjector Needle Depth According to Subcutaneous Tissue Thickness in Patients With Multiple Sclerosis Receiving Subcutaneous Injections of Glatiramer Acetate [O] . Maria Luisa Sánchez Masid, Rosalía Horno Ocaña, María Jesús Díaz Gil, -1

机译：接受皮下注射醋酸格拉替雷的多发性硬化症患者根据皮下组织厚度调节自动注射针深度的患者护理程序
7. Effect of Subcutaneous Injection of Calcium Gluconate on Blood Calcium Concentration and Injection Tissue in Dairy Cattle [O] . Taiki SIMIZU, Kiyoshi TAGUCHI, Akitoyo NISHIKAWA, 2006

机译：皮下注射葡萄糖酸钙对奶牛血钙浓度和注射组织的影响

Measuring Tissue Back-Pressure - In Vivo Injection Forces During Subcutaneous Injection

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