Bisoprolol and Bisoprolol-Valsartan Compatibility Studied by Differential Scanning Calorimetry, Nuclear Magnetic Resonance and X-Ray Powder Diffractometry

Marcin Skotnicki; Juan A. Aguilar; Marek Pyda; Paul Hodgkinson

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Bisoprolol and Bisoprolol-Valsartan Compatibility Studied by Differential Scanning Calorimetry, Nuclear Magnetic Resonance and X-Ray Powder Diffractometry

机译：比索洛尔和比索洛尔-缬沙坦相容性的差示扫描量热法，核磁共振和X射线粉末衍射研究。

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Purpose The objective of this study was to evaluate the thermal behavior of crystalline and amorphous bisoprolol fumarate and its compatibility with amorphous valsartan. This pharmacologically relevant drug combination is a potential candidate for fixed-dose combination formulation.

机译：目的这项研究的目的是评估结晶和无定形富马酸比索洛尔的热行为及其与无定形缬沙坦的相容性。该药理学上相关的药物组合是固定剂量组合制剂的潜在候选者。

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《Pharmaceutical Research》 |2015年第2期|414-429|共16页
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Marcin Skotnicki; Juan A. Aguilar; Marek Pyda; Paul Hodgkinson;
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1. Bisoprolol and Bisoprolol-Valsartan Compatibility Studied by Differential Scanning Calorimetry, Nuclear Magnetic Resonance and X-Ray Powder Diffractometry [J] . Skotnicki Marcin, Aguilar Juan A., Pyda Marek, Pharmaceutical research . 2015,第2期

机译：用差示扫描量热法，核磁共振和X射线粉末衍射法研究比索洛尔和比索洛尔-缬沙坦的相容性
2. H-1 nuclear magnetic resonance spin-lattice relaxation, C-13 magic-angle-spinning nuclear magnetic resonance spectroscopy, differential scanning calorimetry, and x-ray diffraction of two polymorphs of 2,6-di-tert-butylnaphthalene [J] . Beckmann PA., Clemo KM., Slonaker EN., The Journal of Chemical Physics . 2000,第5期

机译：H-1核磁共振自旋晶格弛豫，C-13魔角旋转核磁共振波谱，差示扫描量热法和2，6-二叔丁基萘的两种多晶型物的X射线衍射
3. ~(1)H nuclear magnetic resonance spin-lattice relaxation, ~(13)C magic-angle-spinning nuclear magnetic resonance spectroscopy, differential scanning calorimetry, and x-ray diffraction of two polymorphs of 2,6-di-tert-butylnaphthalene [J] . Peter A. Beckmann, Kendra S. Burbank, Katharine M. Clemo, The Journal of Chemical Physics . 2000,第5期

机译：〜（1）H核磁共振自旋晶格弛豫，〜（13）C魔角旋转核磁共振波谱，差示扫描量热法和2,6-二叔丁基萘的两种多晶型物的X射线衍射
4. Crystallization Kinetics of Fe-B Based Amorphous Alloys Studied In Situ by X-Ray Diffraction and Differential Scanning Calorimetry [C] . P. Tomic, M. Davidovic, S. Batinic Yugoslav Materials Research Society Conference on Progress in Advanced Materials and Processes; 20030915-20030919; Herceg,Novi; YU . 2003

机译：X射线衍射和差示扫描量热法原位研究Fe-B基非晶态合金的结晶动力学
5. The Effects of Functional Ingredients and Frozen Storage on Wheat Dough and Bread Quality Studied Using Time-Domain Nuclear Magnetic Resonance, Dynamic Rheology, and Environmental Scanning Electron Microscopy [D] . Jasrotia, Aswini Kumar Singh. 2010

机译：用时域核磁共振，动态流变学和环境扫描电子显微镜研究官能成分和冷冻储存对小麦面团和面包质量的影响
6. Bisoprolol and Bisoprolol-Valsartan Compatibility Studied by Differential Scanning Calorimetry Nuclear Magnetic Resonance and X-Ray Powder Diffractometry [O] . Marcin Skotnicki, Juan A. Aguilar, Marek Pyda, -1

机译：比索洛尔和比索洛尔-缬沙坦相容性的差示扫描量热法核磁共振和X射线粉末衍射研究。
7. Bisoprolol and bisoprolol-valsartan compatibility studied by differential scanning calorimetry, nuclear magnetic resonance and X-ray powder diffractometry. [O] . Skotnicki Marcin, Aguilar Juan A., Pyda Marek, 2015

机译：通过差示扫描量热法，核磁共振和X射线粉末衍射法研究了比索洛尔和比索洛尔-缬沙坦的相容性。
8. NMR (Sodium Nuclear Magnetic Resonance), DSC (Differential Scanning Calorimetry), TMA, and High Pressure Electrical Conductivity Studies in PPO Complexed with Sodium Perchlorate [R] . Greenbaum, S. G., Pak, Y. S., Wintersgill, M. C., 1987

机译：核磁共振（钠核磁共振），DsC（差示扫描量热法），Tma和ppO与高氯酸钠复合物的高压电导率研究

Bisoprolol and Bisoprolol-Valsartan Compatibility Studied by Differential Scanning Calorimetry, Nuclear Magnetic Resonance and X-Ray Powder Diffractometry

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