Three-dimensional co-culture model of enterocytes and primary enteric neuronal tissue

摘要

The aim of this study was to establish a three-dimensional model of the innervated mucosal barrier using a co-culture of an enterocyte cell line and enteric glial and nerve cells. Such a model might form the basis for further studies of interactions between the single compartments of the bowel wall, as well as of extrinsic influences on intestinal development and plasticity.