Measurement uncertainty of 25-OH vitamin D determination with different commercially available kits: impact on the clinical cut offs

摘要

Summary Due to “measurement uncertainty”, the “true” 25-OH vitamin D (25(OH)D) of a patient (whatever the commercially available assay tested) will be >80 nmol/L if its measured concentration is >100 nmol/L. Thus, if a physician considers that a normal VTD status is a 25(OH)D level ≥80 nmol/L, he should ensure that the patient’s results are ≥100 nmol/L.