A rapid stereocontrolled synthesis of the 3a-hydroxy-pyrrolo-[2,3-b]indole skeleton, a building block for 10b-hydroxypyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-diones

Steven V. Ley; Ed Cleator; Peter R. Hewitt

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A rapid stereocontrolled synthesis of the 3a-hydroxy-pyrrolo-[2,3-b]indole skeleton, a building block for 10b-hydroxypyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-diones

机译：快速立体控制合成3a-羟基-吡咯并[2,3-b]吲哚骨架，10b-羟基吡嗪并[1'，2'：1,5]吡咯并[2,3-b]吲哚- 1,4-二酮

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A two-step selenocyclisation-oxidative deselenation sequence was used to establish the 3a-hydroxy-pyrrolo-[2,3-b]indole core; these tricycles were used as effective precursors to 10b-hydroxy-pyrazino[1',2':1,5]pyrrolo-[2,3-b]indole-1,4-diones.

机译：使用两步硒环化-氧化脱硒序列建立3a-羟基-吡咯并-[2,3-b]吲哚核。这些三环用作10b-羟基-吡嗪并[1'，2'：1,5]吡咯并-[2,3-b]吲哚-1,4-二酮的有效前体。

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《Organic & biomolecular chemistry》 |2003年第20期|p. 3492-3494|共3页
作者
Steven V. Ley; Ed Cleator; Peter R. Hewitt;
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Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK CB2 1EW;

Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK CB2 1EW;

Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK CB2 1EW;

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正文语种 eng
中图分类物理化学（理论化学）、化学物理学;
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A rapid stereocontrolled synthesis of the 3a-hydroxy-pyrrolo-[2,3-b]indole skeleton, a building block for 10b-hydroxypyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-diones

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