Lewis-acid assisted cross metathesis of acrylonitrile with functionalized olefins catalyzed by phosphine-free ruthenium carbene complex

摘要

The exchange of the PPh_3 ligand in the complex [1,3-bis(2,6-dimethylphenyl)4,5-dihydroimidazol-2-ylidene](PPh_3)-(Cl)_2Ru=CHPh(7)for a pyridine ligand at ambient temperature leads to the formation of the stable phosphine-free carbene ruthenium complex [1,3-bis(2,6-dimethylphenyl)4,5-dihydroimidazol-2-ylidene](C_5H_5N)_2(Cl)_2 Ru=CHPh(8).The resulted ruthenium complex exhibits highly catalytic activity for the cross metathesis of acrylonitrile with various functionalized olefins under mild conditions,and its activity can be further improved by the addition of a Lewis acid such as Ti(O~iPr)_4.In the mixture products,the Z-isomer predominates.