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FeCl_3 or MeSO_3H-promoted multicomponent reactions for facile synthesis of structurally diverse furan analoguesf

机译:FeCl_3或MeSO_3H促进的多组分反应,可轻松合成结构多样的呋喃类似物f

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摘要

An intriguing conversion of arylglyoxal, cyclic dicarbonyl compounds and phenols to diverse furan analogues under FeCl3 or MeSO3H catalysis is reported. Utilizing this synthetic protocol, a variety of furan analogues could be easily obtained in moderate to good yields with different substituted patterns by varying the reaction medium. Atom-economical characteristics and mild conditions of this method are in accord with the concept of modern green chemistry.
机译:据报道,在FeCl3或MeSO3H催化下,芳基乙二醛,环状二羰基化合物和酚转化为各种呋喃类似物的过程非常有趣。利用该合成方案,通过改变反应介质,可以容易地以中等至良好的产率获得具有不同取代模式的多种呋喃类似物。该方法的原子经济特性和温和条件符合现代绿色化学的概念。

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  • 来源
    《Organic & biomolecular chemistry》 |2018年第23期|4279-4287|共9页
  • 作者单位

    Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology,College of Pharmaceutical Sciences, Zhejiang University of Technology, Chao Wang Road 18th, 310014, Hangzhou, China.;

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