Correlation of expression of hypoxia-related proteins with prognosis in oral squamous cell carcinoma patients

A. W. Eckert; M. Kappler; J. Schubert; H. Taubert

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Correlation of expression of hypoxia-related proteins with prognosis in oral squamous cell carcinoma patients

机译：口腔鳞癌患者缺氧相关蛋白的表达与预后的关系

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Hypoxia plays a major role in tumor progression, therapy resistance and for prognosis of oral squamous cell carcinoma (OSCC). The crucial step as a response to hypoxia is the activation and stabilization of the alpha subunit of hypoxia inducible factor 1 (HIF-1α).

机译：缺氧在肿瘤进展，治疗耐药性以及口腔鳞状细胞癌（OSCC）的预后中起主要作用。应对缺氧的关键步骤是缺氧诱导因子1（HIF-1α）的α亚基的激活和稳定。

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来源
《Oral and Maxillofacial Surgery》 |2012年第2期|p.189-196|共8页
作者
A. W. Eckert; M. Kappler; J. Schubert; H. Taubert;
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作者单位

Department of Oral and Maxillofacial Plastic Surgery, Martin-Luther-University Halle-Wittenberg, E.-Grube-Str. 40, 06120, Halle, Saale, Germany;

Department of Oral and Maxillofacial Plastic Surgery, Martin-Luther-University Halle-Wittenberg, E.-Grube-Str. 40, 06120, Halle, Saale, Germany;

Department of Oral and Maxillofacial Plastic Surgery, Martin-Luther-University Halle-Wittenberg, E.-Grube-Str. 40, 06120, Halle, Saale, Germany;

Division of Molecular Urology, Clinic of Urology FA University Hospital Erlangen, Hartmannstr. 14, 91054, Erlangen, Germany;

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原文格式 PDF
正文语种 eng
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关键词
Oral squamous cell carcinoma; Hypoxia; HIF; Pathways;

机译：口腔鳞癌;缺氧;HIF;途径;

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1. Correlation of expression of hypoxia-related proteins with prognosis in oral squamous cell carcinoma patients [J] . EckertA.W., KapplerM., SchubertJ., Oral and maxillofacial surgery. . 2012,第2期

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2. P53 Protein Expression and its Correlation with Prognosis of Oral Squamous Cell Carcinoma [J] . Farhadi s, Mashhadi abbas F, Montazeri hedeshi R Journal of Research in Dental Sciences . 2013,第2期

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3. Correlation between secreted protein acidic and rich in cysteine protein expression and the prognosis of postoperative patients exhibiting esophageal squamous cell carcinoma [J] . Wu Jian, Zhang Jin-Rong, Jiang Xue-Qiu, Molecular medicine reports . 2017,第3aPta2期

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Correlation of expression of hypoxia-related proteins with prognosis in oral squamous cell carcinoma patients

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